Joshua Karty hit a 37-yard field goal with 2 seconds to play, and the Los Angeles Rams staged a spectacular late rally for a 27-24 victory over the San Francisco 49ers.

The 49ers attempted a seven-lateral desperation play in the final seconds and reached Rams territory before Jake Brendel’s toss to Brandon Aiyuk bounded out of bounds to end one of the 49ers’ most frustrating losses in years. It was also their first regular-season defeat at SoFi Stadium in five years.

The Rams trailed by 10 points with less than 7 minutes to go but rallied to score 13 points, culminated by a field goal with 2 seconds left to beat the 49ers.