Background: Fibromyalgia syndrome (FMS) is a multidimensional chronic disorder characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, cognitive dysfunction, depressive episodes ...

Objectives We aimed to assess the expression of the CCL24 chemokine in systemic sclerosis (SSc) and to evaluate the possible pathogenic implications of the CCL24/CCR3 axis using both in vitro and in ...

Material and Methods The murine macrophage cell line RAW264.7 was preincubated for 1 hr with increasing concentrations (10 – 500 µM) of the H 2 S donors termed 5a, 5b, 8a and 8l in the presence of 1 ...

Background Since the publication of the EULAR recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several randomised clinical trials ...

Study of the genetics of rheumatoid arthritis (RA) began about four decades ago with the discovery of HLA-DRB1. Since the beginning of this century, a number of non-HLA risk loci have been identified ...

Correspondence to Dr Arani Vivekanantham, Centre for Epidemiology Versus Arthritis, University of Manchester, Manchester, M13 9PL, UK; arani.vivekanantham{at}postgrad.manchester.ac.uk If you wish to ...

Correspondence to Veerle F A M Derksen, Rheumatology, Leiden University Medical Center, Leiden 2300 RC, Netherlands; v.f.a.m.derksen{at}lumc.nl If you wish to reuse ...

While biologic disease-modifying antirheumatic drugs (bDMARDs) have transformed outcomes of people with rheumatoid arthritis (RA), a proportion of patients are refractory to multiple bDMARDs.

Objectives Ultrasound of temporal and axillary arteries may reveal vessel wall inflammation in patients with giant cell arteritis (GCA). We developed a ultrasound scoring system to quantify the extent ...

Objectives Hospitalisation is a risk factor for flares in people with gout. However, the predictors of inpatient gout flare are not well understood. The aim of this study was to develop a prediction ...

Correspondence to Arieke Suzanna Berendina Kampstra, Rheumatology, Leids Universitair Medisch Centrum, Leiden 2333 ZA, Netherlands; a.s.b.kampstra{at}lumc.nl Objectives Autoantibodies against ...

Objectives We aim to investigate the genetic basis of a case of late-onset autoinflammatory disease characterised by arthritis, recurrent fever and skin rashes. Methods We performed whole-exome/genome ...