The intracellular bacterial pathogen Coxiella burnetii secretes an effector protein, CbEPF1, which manipulates LD metabolism ...
The systemic regulation of metabolic dysfunction-associated liver disease remains poorly understood. In this issue, Hsiao et ...
The past decade has seen a tremendous increase of genetic sequence data for biodiversity assessments and research.
The time bomb of misinformation and disinformation will have exploded, taking with it our ability to think for ourselves.
To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...
The liver function in post-cardiac arrest brain injury is not known and was investigated in a pig model of global cerebral ...
How the hydrolytic activity of mitochondrial ATP synthase is modulated during brown adipose tissue (BAT) thermogenesis ...
Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy
RPE-1 cells adapt to aneuploidy in vitro, a process characterized by reduced CIN and inflammation. This study shows that this ...
MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...
Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...
Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...
TBK1-Zyxin signaling controls tumor-associated macrophage recruitment to mitigate antitumor immunity
Although the role of innate immune sensing pathways is well-studied in the pathogenesis of malignancies, whether they ...
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